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Duvelisib Chemical Structure

Duvelisib

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP07042CAS No. ：1201438-56-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1201438-56-3 Cat. No. BCP07042
Name Duvelisib
Synonyms IPI-145；INK1197; IPI 145; IPI145; INK-1197; INK 1197;
SMILES O=C1N(C2=CC=CC=C2)C([C@@H](NC3=C4N=CNC4=NC=N3)C)=CC5=C1C(Cl)=CC=C5
Chemical Name
Formula C22H17ClN6O M. Wt 416.86
Purity 98% Storage Store at 4-8°C
Description Duvelisib, also known as IPI-145 and INK-1197, is an orally bioavailable, highly selective and potent small molecule inhibitor of the delta and gamma isoforms of phosphoinositide-3 kinase (PI3K) with potential immunomodulating and antineoplastic activities. Upon administration, PI3K delta/gamma inhibitor IPI 145 prevents the activation of the PI3K delta/gamma-mediated signaling pathways which may lead to a reduction in cellular proliferation in PI3K delta/gamma-expressing tumor cells. Unlike other isoforms of
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H-NMR LCMS
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