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BKM-120 Chemical Structure

BKM-120

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP06726CAS No. ：1202777-78-3Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1202777-78-3 Cat. No. BCP06726
Name BKM-120
Synonyms BKM120; BKM 120; NVP-BKM120;
SMILES
Chemical Name
Formula C18H21F3N6O2 M. Wt 410.39
Purity 98% Storage Store at 4-8°C
Description BKM120 (NVP-BKM120) is a novel phosphatidylinositol 3-kinase (PI3K) inhibitor and is currently being investigated in phase I clinical trials in solid tumors. Unlike other inhibitors, it does not inhibit the related kinases-mTOR and Vps34. BKM120 (NVP-BKM120) has shown significant cell growth inhibition and induction of apoptosis in a variety of tumor cell lines as well as in animal models, it decreases the cellular levels of p-Akt in mechanistic models and relevant tumor cell lines, as well as d
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