Icotinib Hydrochloride New
Data Sheet
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| CAS No. | 1204313-51-8 | Cat. No. | BCP06306 |
| Related Products | 610798-31-7（Icotinib） | ||
| Name | Icotinib Hydrochloride | ||
| Synonyms | Icotinib HCl;BPI2009; BPI 2009; BPI-2009;BPI-2009H; | ||
| SMILES | C#CC1=CC(=CC=C1)NC2=NC=NC3=CC4=C(C=C32)OCCOCCOCCO4.Cl | ||
| Chemical Name | |||
| Formula | C22H21N3O4.HCl | M. Wt | 427.89 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Icotinib Hydrochloride is the hydrochloride salt form of icotinib, an orally available quinazoline-based inhibitor of epidermal growth factor receptor (EGFR), with potential antineoplastic activity. Icotinib selectively inhibits the wild-type and several mutated forms of EGFR tyrosine kinase. This may lead to an inhibition of EGFR-mediated signal transduction and may inhibit cancer cell proliferation. EGFR, a receptor tyrosine kinase, has been upregulated in a variety of cancer cell types. | ||
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