21R-Argatroban New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 121785-71-5 | Cat. No. | BCP12713 |
| Name | 21R-Argatroban | ||
| Synonyms | |||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H36N6O5S | M. Wt | 508.63 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | 21R-Argatroban is the 21R-stereoisomer of Argatroban.Argatroban is an anticoagulant that is a direct thrombin inhibitor. Argatroban was approved in 2000 for prophylaxis or treatment of thrombosis in patients with heparin-induced thrombocytopenia (HIT). Argatroban is a direct thrombin inhibitor that reversibly binds to the thrombin active site. Argatroban exerts its anticoagulant effects by inhibiting thrombin-catalyzed or -induced reactions, including fibrin formation; activation of coagulation factors V, VIII, and XIII; activation of protein C; and platelet aggregation. Argatroban inhibits thrombin with an inhibition constant (Ki) of 0.04 μM. | ||
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