AVN-492
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CAS No. | 1220646-23-0 | Cat. No. | BCP23511 |
Name | AVN-492 | ||
Synonyms | AVN 492; AVN492; | ||
SMILES | |||
Chemical Name | |||
Formula | C17H21N5O2S | M. Wt | 359.45 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AVN-492 is a potent and selective 5-HT6R Antagonist. The affinity of AVN-492 to bind to 5-HT6R (Ki = 91 pM) was more than three orders of magnitude higher than that to bind to the only other target, 5-HT2BR, (Ki = 170 nM). AVN-492 demonstrates good in vitro and in vivo ADME profile with high oral bioavailability and good brain permeability in rodents. |
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