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CC-223 Chemical Structure

CC-223

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP09953CAS No. ：1228013-30-6Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1228013-30-6 Cat. No. BCP09953
Name CC-223
Synonyms CC 223;CC223;Onatasertib;
SMILES OC(C)(C)C(N=C1)=CC=C1C(N=C2N3[C@@H]4CC[C@H](CC4)OC)=CN=C2NCC3=O
Chemical Name
Formula C21H27N5O3 M. Wt 397.47
Purity 98% Storage Store at 4-8°C
Description Onatasertib, also known as CC-223, is an orally available inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor CC-223 inhibits the activity of mTOR, which may result in the induction of tumor cell apoptosis and a decrease in tumor cell proliferation. mTOR, a serine/threonine kinase that is upregulated in a variety of tumors, plays an important role downstream in the PI3K/AKT/mTOR signaling pathway, which is frequently dysregulated in human cancers.
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