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CAS No. | 1229705-06-9 | Cat. No. | BCP11659 |
Name | Idasanutlin | ||
Synonyms | RG-7388;RG 7388;RG7388; RO5503781; RO-5503781; RO 5503781; | ||
SMILES | O=C(O)C1=CC=C(NC([C@@H]2N[C@@H](CC(C)(C)C)[C@](C#N)(C3=CC=C(Cl)C=C3F)[C@H]2C4=CC=CC(Cl)=C4F)=O)C(OC)=C1 | ||
Chemical Name | |||
Formula | C31H29Cl2F2N3O4 | M. Wt | 616.48 |
Purity | 98 | Storage | Store at 4-8°C |
Description | RG7388 showed all the characteristics expected of an MDM2 inhibitor in terms of speci?c binding to the target, mechanistic outcomes resulting from activation of the p53 pathway, and in vivo cacy. Although the cellular mechanism of action of RG7388 is identical to that of RG7112, it is much more potent and selective. |
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