Derazantinib

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP29103CAS No. ：1234356-69-4Purity：98%

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Chemical Properties&Biological Activity

CAS No.	1234356-69-4	Cat. No.	BCP29103
Name	Derazantinib
Synonyms	ARQ087;ARQ-087;ARQ 087;
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Chemical Name
Formula	C29H29FN4O	M. Wt	468.57
Purity	98%	Storage	Store at 4-8°C
Description	Derazantinib, also known as ARQ-087, is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. FGFR inhibitor ARQ 087 binds to and potently inhibits the activity of FGFR subtypes 1, 2 and 3. This may result in the inhibition of FGFR-mediated signal transduction pathways, tumor cell proliferation, tumor angiogenesis and tumor cell death in FGFR-overexpressing tumor cells. FGFR, a receptor tyrosine kinase, is upregulated in many tumor cell types and plays a key role in tumor cellular proliferation, differentiation, angiogenesis and survival.

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