BMS-986020
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CAS No. | 1257213-50-5 | Cat. No. | BCP19107 |
Name | BMS-986020 | ||
Synonyms | BMS 986020;BMS986020; AP-3152 free acid; AM152; AM 152; AM-152; | ||
SMILES | O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O | ||
Chemical Name | |||
Formula | C29H26N2O5 | M. Wt | 482.53 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BMS-986020, also known as AM152 , is a potent and selective LPA1 antagonist. BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions like cell proliferation, platelet aggregation, smooth muscle contraction, chemotaxis, and tumor cell invasion, among others. |
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