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BMS-986020 Chemical Structure

BMS-986020

Data Sheet For research use only. Not for human use.
Cat. No. :BCP19107CAS No. :1257213-50-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1257213-50-5 Cat. No. BCP19107
Name BMS-986020
Synonyms BMS 986020;BMS986020; AP-3152 free acid; AM152; AM 152; AM-152;
SMILES O=C(C1(C2=CC=C(C3=CC=C(C4=C(NC(O[C@@H](C5=CC=CC=C5)C)=O)C(C)=NO4)C=C3)C=C2)CC1)O
Chemical Name
Formula C29H26N2O5 M. Wt 482.53
Purity 98% Storage Store at 4-8°C
Description BMS-986020, also known as AM152 , is a potent and selective LPA1 antagonist. BMS-986020 is in Phase 2 clinical development for treating idiopathic pulmonary fibrosis. BMS-986020 selectively inhibits the LPA receptor, which is involved in binding of the signaling molecule lysophosphatidic acid, which in turn is involved in a host of diverse biological functions like cell proliferation, platelet aggregation, smooth muscle contraction, chemotaxis, and tumor cell invasion, among others.
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