Amsilarotene

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP06502CAS No. ：125973-56-0Purity：98%

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Chemical Properties&Biological Activity

CAS No.	125973-56-0	Cat. No.	BCP06502
Name	Amsilarotene
Synonyms	TAC-101;TAC101;TAC 101;AM 555S;AM-555S;
SMILES
Chemical Name
Formula	C20H27NO3Si2	M. Wt	385.6
Purity	98%	Storage	Store at 4-8°C
Description	Amsilarotene ( TAC-101) is a retinobenzoic acid with potential antineoplastic activity. TAC-101 inhibits retinoblastoma-gene product (RB) phosphorylation and increases the presence of 2 cyclin-dependent kinase (CDK) inhibitors, resulting in cell cycle arrest. This agent also causes a cytotoxic decline in cyclin A and thymidylate synthase expression.

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