BAPTA-AM
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CAS No. | 126150-97-8 | Cat. No. | BCP06681 |
Name | BAPTA-AM | ||
Synonyms | |||
SMILES | |||
Chemical Name | |||
Formula | C34H40N2O18 | M. Wt | 764.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | The BAPTA, Free acid (sc-201508) is not cell permeable and is only useful for manipulating extracellular Ca2+ levels, BAPTA/AM can be used with a wide variety of cells, where it is hydrolyzed by cytosolic esterases and trapped intracellularly. Experiments have shown that BAPTA/AM abolishes vitamin D3-induced increase in intracellular Ca2+, and may induce inactivation of protein kinase C. Has also been shown to inhibit thapsigargin-induced apoptosis in rat thymocytes. |
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