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HS-173 Chemical Structure

HS-173

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP09225CAS No. ：1276110-06-5Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1276110-06-5 Cat. No. BCP09225
Name HS-173
Synonyms HS173; HS 173;
SMILES
Chemical Name
Formula C21H18N4O4S M. Wt 422.46
Purity 98% Storage Store at 4-8°C
Description HS-173 is a potent PI3Kα inhibitor with potential anticancer activity. HS-173 inhibited the PI3K signaling pathway, and showed anti-proliferative effects on cancer cells. Also, HS-173 induced cell cycle arrest at the G(2)/M phase and apoptosis. In addition, HS-173 decreased the expression HIF-1α and VEGF which play an important role in angiogenesis. This effect was confirmed by the suppression of tube formation and migration assay in vitro. Furthermore, HS-173 diminished blood vessel formation
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