DSM265
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1282041-94-4 | Cat. No. | BCP17584 |
| Name | DSM265 | ||
| Synonyms | DSM-265; DSM 265; | ||
| SMILES | FS(F)(F)(F)(C1=CC=C(NC2=CC(C)=NC3=NC(C(F)(F)C)=NN23)C=C1)F | ||
| Chemical Name | |||
| Formula | C14H12F7N5S | M. Wt | 415.33 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | DSM265 is a long-duration, potent and selective dihydroorotate dehydrogenase (DHODH)) inhibitor. DSM265 is potential useful for the prevention and treatment of malaria. DSM265 is the first DHODH inhibitor to reach clinical development for treatment of malaria. DSM265 is highly selective toward DHODH of the malaria parasite Plasmodium, efficacious against both blood and liver stages of P. falciparum, and active against drug-resistant parasite isolates. DSM265 has advantages over current treatment options that are dosed daily or are inactive against the parasite liver stage. | ||
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