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Darolutamide Chemical Structure

Darolutamide

Data Sheet For research use only. Not for human use.
Cat. No. :BCP15972CAS No. :1297538-32-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1297538-32-9 Cat. No. BCP15972
Name Darolutamide
Synonyms ODM201;ODM 201;ODM-201; BAY-1841788; BAY1841788; BAY 1841788;
SMILES CC(CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=NNC(=C3)C(C)O
Chemical Name
Formula C19H19ClN6O2 M. Wt 398.85
Purity 98% Storage Store at 4-8°C
Description Darolutamide is a formulation containing an androgen receptor (AR) antagonist with potential antineoplastic activity. Darolutamide binds to ARs in target tissues; subsequently, inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells.
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