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CAS No. | 1297538-32-9 | Cat. No. | BCP15972 |
Name | Darolutamide | ||
Synonyms | ODM201;ODM 201;ODM-201; BAY-1841788; BAY1841788; BAY 1841788; | ||
SMILES | CC(CN1C=CC(=N1)C2=CC(=C(C=C2)C#N)Cl)NC(=O)C3=NNC(=C3)C(C)O | ||
Chemical Name | |||
Formula | C19H19ClN6O2 | M. Wt | 398.85 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Darolutamide is a formulation containing an androgen receptor (AR) antagonist with potential antineoplastic activity. Darolutamide binds to ARs in target tissues; subsequently, inhibiting androgen-induced receptor activation and facilitating the formation of inactive complexes that cannot translocate to the nucleus. This prevents binding to and transcription of AR-responsive genes that regulate prostate cancer cell proliferation. This ultimately leads to an inhibition of growth in AR-expressing prostate cancer cells. |
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