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CAS No. | 131888-54-5 | Cat. No. | BCP20243 |
Name | YM 264 | ||
Synonyms | YM-264;YM264; | ||
SMILES | CC(C)(CCN1CCN(CC1)C(=O)C2CSC(N2)C3=CN=CC=C3)C4=CC=CC=C4.C(=CC(=O)O)C(=O)O | ||
Chemical Name | |||
Formula | C24H32N4OS.C4H4O4 | M. Wt | 540.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | YM-264 is a selective, potent and orally active platelet-activating factor antagonist potentially for the treatment of asthma. YM264 inhibited [3H] platelet-activating factor binding to rabbit platelet membranes with a pKi value of 8.85. YM264 inhibited the platelet-activating factor-induced human, rabbit and guinea-pig platelet aggregation with pA2 values of 8.68, 8.33 and 8.14, respectively. ight in a parallel manner. |
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