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Fudosteine Chemical Structure

Fudosteine

Data Sheet For research use only. Not for human use.
Cat. No. :BCP11478CAS No. :13189-98-5Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 13189-98-5 Cat. No. BCP11478
Name Fudosteine
Synonyms SS-320A; SS 320A; SS320A;Cleanal;Spelear;
SMILES
Chemical Name
Formula C6H13NO3S M. Wt 179.24
Purity 98% Storage Store at 4-8°C
Description Fudosteine is a cysteine derivative that is used as an expectorant in chronic bronchial inflammatory disorders. The administration of fudosteine during the challenge with ovalbumin prevented the development of airway hyperresponsiveness and accumulation of lymphocytes in the airways. Eotaxin, IL-4, and TGF-β levels and the relative intensity of matrix metalloproteinase-2 and matrix metalloproteinase-9 (MMP-2 and MMP-9) in BAL fluid were reduced by the fudosteine treatment; however, the number of eosinophils in BAL fluid and serum IgE levels did not change. The expression of TGF-β, the development of goblet cell hyperplasia, subepithelial collagenization, and basement membrane thickening were also reduced by the fudosteine treatment.
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