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CAS No. | 1320288-19-4 | Cat. No. | BCP08635 |
Name | UNC0631 | ||
Synonyms | UNC 0631; UNC-0631; | ||
SMILES | COC1=CC2=C(NC3CCN(CC4CCCCC4)CC3)N=C(N5CCN(C(C)C)CCC5)N=C2C=C1OCCCN6CCCCC6 | ||
Chemical Name | |||
Formula | C37H61N7O2 | M. Wt | 635.93 |
Purity | 98% | Storage | Store at 4-8°C |
Description | UNC-0631 is a novel G9a inhibitor with excellent potency in a variety of cell lines and excellent separation of functional potency versus cell toxicity. Protein lysine methyltransferase G9a plays key roles in the transcriptional repression of a variety of genes via dimethylation of lysine 9 on histone H3 (H3K9me2) of chromatin as well as dimethylation of nonhistone proteins including tumor suppressor p53. |
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