Flutamide
Data Sheet
For research use only. Not for human use.
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| CAS No. | 13311-84-7 | Cat. No. | BCP23006 |
| Name | Flutamide | ||
| Synonyms | SCH13521; SCH-13521; SCH 13521; Flucinom; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C11H11F3N2O3 | M. Wt | 276.21 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Flutamide, also known as SCH13521, is a toluidine derivative and nonsteroidal antiandrogen that is structurally related to bicalutamide and nilutamide. Flutamide and its more potent active metabolite 2-hydroxyflutamide competitively block dihydrotestosterone binding at androgen receptors, forming inactive complexes which cannot translocate into the cell nucleus. Formation of inactive receptors inhibits androgen-dependent DNA and protein synthesis, resulting in tumor cell growth arrest or transient tumor regression. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). | ||
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