SAR7334 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1333210-07-3 | Cat. No. | BCP11028 |
| Name | SAR7334 | ||
| Synonyms | SAR-7334; SAR 7334; TRCP6 inhibitor; | ||
| SMILES | C1CC(CN(C1)C2CC3=CC=CC=C3C2OC4=C(C=C(C=C4)C#N)Cl)N | ||
| Chemical Name | |||
| Formula | C21H22ClN3O | M. Wt | 367.87 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | SAR7334 is a novel, highly potent and bioavailable inhibitor of TRPC6 channels that opens new opportunities for the investigation of TRPC channel function in vivo. SAR7334 inhibited TRPC6, TRPC3 and TRPC7-mediated Ca(2+) influx into cells with IC50 s of 9.5, 282 and 226 nM, whereas TRPC4 and TRPC5-mediated Ca(2+) entry was not affected. | ||
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