Pagoclone
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CAS No. | 133737-32-3 | Cat. No. | BCP28850 |
Name | Pagoclone | ||
Synonyms | (+)-RP-59037;CI-1043; IP-456; RP-62955; RP-59037; CI1043; IP456; RP62955; RP59037. Bextra; | ||
SMILES | |||
Chemical Name | |||
Formula | C23H22ClN3O2 | M. Wt | 407.9 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pagoclone, also known as CI-1043; IP-456; RP-62955; RP-59037, is a GABA receptor agonist potentially for the treatment of stuttering, panic disorder and generalised anxiety. It binds with roughly equivalent high affinity (0.7–9.1 nM) to the benzodiazepine binding site of human GABAA receptors containing either an α1, α2, α3 or α5 subunit. It is a partial agonist at α1-, α2- and α5-containing GABAA receptors and a full agonist at receptors containing an α3 subunit. |
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