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GSK2656157 Chemical Structure

GSK2656157

Data Sheet For research use only. Not for human use.
Cat. No. :BCP09007CAS No. :1337532-29-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1337532-29-2 Cat. No. BCP09007
Name GSK2656157
Synonyms GSK 2656157; GSK-2656157;
SMILES
Chemical Name
Formula C23H21FN6O M. Wt 416.45
Purity 98% Storage Store at 4-8°C
Description GSK2656157 is is highly selective for PERK with IC50 values >100 nM against a panel of 300 kinases. GSK2656157 inhibits PERK activity in cells with an IC50 in the range of 10-30 nM by inhibition of stress-induced PERK autophosphorylation, eIF2α substrate phosphorylation, together with corresponding decreases in ATF4 and CHOP proteins in multiple cell lines.
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