CFI-400945 free base
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1338806-73-7 | Cat. No. | BCP18988 |
| Name | CFI-400945 free base | ||
| Synonyms | CFI 400945 free base;CFI400945 free base; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C33H34N4O3 | M. Wt | 534.65 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | In vitro: Cancer cells treated with CFI-400945 exhibit effects consistent with PLK4 kinase inhibition, including dysregulated centriole duplication, mitotic defects, and cell death.CFI-400945 treatment lead to aberrant centriole duplication and abnormal mitoses in vitro that ultimately causes cell death or cell-cycle arrest. In vivo: Oral administration of CFI-400945 to mice bearing human cancer xenografts results in the significant inhibition of tumor growth at doses that are well tolerated.[1]Oral administration of CFI-400945 was well tolerated in multiple xenograft models and mouse strains, and had favorable pharmacokinetics. CFI-400945 also had single-agent antitumor activity. | ||
Recommend Products
More >
-
Onvansertib fumarate
Cat. No.：BCP49273
No.：1263293-37-3
Product Details -
TC-S 7005
Cat. No.：BCP48202
No.：1082739-92-1
Product Details -
-
ON1231320
Cat. No.：BCP40722
No.：1312471-39-8
Product Details -
-
CFI-400437
Cat. No.：BCP29569
No.：1247000-76-5
Product Details -
TAK-960 hydrochloride
Cat. No.：BCP28992
No.：1137868-96-2
Product Details -
CFI-400945 fumarate
Cat. No.：BCP25931
No.：1616420-30-4
Product Details -
-
Mps1-in-2
Cat. No.：BCP19164
No.：1228817-38-6
Product Details -
Centrinone
Cat. No.：BCP17384
No.：1798871-30-3
Product Details -
-
SBE 13 hydrochloride
Cat. No.：BCP23836
No.：1052532-15-6
Product Details -
LFM-A13(Z)
Cat. No.：BCP12817
No.：244240-24-2
Product Details -
Onvansertib
Cat. No.：BCP28066
No.：1034616-18-6
Product Details -
-
-
-
-
Rigosertib
Cat. No.：BCP08296
No.：592542-59-1
Product Details
Tags:CFI-400945 free base supplier,CFI-400945 free base purchase,CFI-400945 free base manufacturer,CFI-400945 free base distributor,CFI-400945 free base cost,CFI-400945 free base buy,CFI-400945 free base for sale