ML240 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1346527-98-7 | Cat. No. | BCP25527 |
| Name | ML240 | ||
| Synonyms | ML 240;ML-240; | ||
| SMILES | COC1=CC=CC2=C1N=C(N=C2NCC3=CC=CC=C3)N4C5=CC=CC=C5N=C4N | ||
| Chemical Name | |||
| Formula | C23H20N6O | M. Wt | 396.45 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ML240 is a ATP-competitive inhibitor of p97 ATPase (IC50 = 110 nM). p97 is a homohexamer with each protomer containing a protein−protein interaction domain at the N-terminus, a D1 ATPase/hexamerization domain, and the catalytic D2 ATPase domain. p97 inhibitors could have improved therapeutic potential in tumor types currently treated by proteasome inhibitors. | ||
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