Olmutinib
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1353550-13-6 | Cat. No. | BCP16733 |
| Name | Olmutinib | ||
| Synonyms | BI1482694;BI 1482694;BI-1482694;HM 61713;HM-61713;HM61713; | ||
| SMILES | C=CC(NC1=CC=CC(OC2=C3C(C=CS3)=NC(NC4=CC=C(N5CCN(C)CC5)C=C4)=N2)=C1)=O | ||
| Chemical Name | |||
| Formula | C26H26N6O2S | M. Wt | 486.59 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Olmutinib is an Epidermal growth factor receptor (EGFR) antagonist.Olmutinib(HM61713) is a third generation epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor that inhibits both EGFR activating and T790M resistance mutations, while sparing wild-type EGFR. It has been investigated in Phase II clinical trials in patients with EGFR T790M mutation-positive non-small cell lung cancer (NSCLC), who developed resistance to earlier generations of EGFR tyrosine kinase inhibitor therapy. | ||
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