Foropafant New
Data Sheet
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| CAS No. | 136468-36-5 | Cat. No. | BCP13236 |
| Name | Foropafant | ||
| Synonyms | SR-27417; SR 27417; SR27417; SR-27417A; | ||
| SMILES | CC(C)C1=CC(=C(C(=C1)C(C)C)C2=CSC(=N2)N(CCN(C)C)CC3=CN=CC=C3)C(C)C | ||
| Chemical Name | |||
| Formula | C28H40N4S | M. Wt | 464.71 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Foropafant, also known as SR-27417; SR-27417A, is a potent platelet activating factor (PAF) inhibitor potentially for the treatment of asthma and allergic rhinitis (AR). SR 27417 inhibits in a dose-dependent manner the hypotensive effect of PAF in rats. It protected rats with an ED50 value of 6 +/- 2 micrograms/kg (n = 6), when given i.v., 1 min before PAF administration. PAF plays a major role in anaphylactic shock. SR 27417 may be an effective prophylactic as well as a potent curative drug in this pathology. | ||
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