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RG-14620 Chemical Structure

RG-14620

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP20770CAS No. ：136831-49-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 136831-49-7 Cat. No. BCP20770
Name RG-14620
Synonyms RG14620; RG-14620; TYRPHOSTIN RG 14620;
SMILES N#C/C(C1=CC=CN=C1)=C/C2=CC(Cl)=CC(Cl)=C2
Chemical Name
Formula C14H8Cl2N2 M. Wt 275.13
Purity 98% Storage Store at 4-8°C
Description RG-14620 is an EGFR inhibitor. It is a non-phenolic tyrphostin analog, which is selective for the EGF receptor and long acting. It inhibits EGF-stimulated HER14 cell proliferation (IC50=3 μM) as well as tumor growth in vivo.
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