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GSK2636771 Chemical Structure

GSK2636771

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP05688CAS No. ：1372540-25-4Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1372540-25-4 Cat. No. BCP05688
Name GSK2636771
Synonyms GSK 2636771;GSK-2636771;
SMILES
Chemical Name
Formula C22H22F3N3O3 M. Wt 433.42
Purity 98% Storage Store at 4-8°C
Description GSK-2636771 shows selectively inhibitory activity in PTEN null cell lines (human prostate adenocarcinoma PC-3 and breast cancer HCC70) with EC50 of 36 nM and 72 nM, respectively. GSK2636771 significantly decreases cell viability in p110β-reliant PTEN-deficient PC3 prostate and BT549 and HCC70 breast cancer cell lines, and leads to a marked decrease of AKT phosphorylation only in the control prostate and breast cancer cell lines.
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LCMS H-NMR
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