ACY-738
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1375465-91-0 | Cat. No. | BCP16151 |
| Name | ACY-738 | ||
| Synonyms | ACY 738;ACY738; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C14H14N4O2 | M. Wt | 270.29 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: ACY-738 significantly reduces the number of marbles buried, to a similar degree as a non-sedating (10 mg/kg) dose of the common anxiolytic CDP. in vivo: ACY-738 induces dramatic increases in α-tubulin acetylation in brain and stimulate mouse exploratory behaviors in novel, but not familiar environments. In addition, ACY-738 given acutely at a dose of 50?mg/kg significantly decreased latency to eat in the NIH test, although this effect was not as potent as that of CDP. In the EPM, a test sensitive to anxiolytics but not antidepressants, neither ACY-738 produces behavioral changes, whereas CDP markedly increased the time in the open arms of the maze. | ||
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