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BAY-1082439 Chemical Structure

BAY-1082439

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP19095CAS No. ：1375469-38-7Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1375469-38-7 Cat. No. BCP19095
Name BAY-1082439
Synonyms BAY10-82439; BAY 10-82439; BAY-10-82439;BAY 1082439;BAY1082439;
SMILES O=C(C1=CC=CN=C1C)NC2=NC3=C(C=CC(OC[C@](O)CN4CCOCC4)=C3OC)C5=NCCN25
Chemical Name
Formula C25H30N6O5 M. Wt 494.55
Purity 98% Storage Store at 4-8°C
Description BAY1082439 is an orally bioavailable inhibitor of the class I phosphoinositide 3-kinase (PI3K) alpha and beta isoforms with potential antineoplastic activity. PI3K alpha/beta inhibitor BAY1082439 selectively inhibits both PI3K alpha, including mutated forms of PIK3CA, and PI3K beta in the PI3K/Akt/mTOR pathway, which may result in tumor cell apoptosis and growth inhibition in PI3K-expressing and/or PTEN-driven tumor cells. By specifically targeting class I PI3K alpha and beta, this agent may be more efficacious and less toxic than pan PI3K inhibitors.
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