Pinometostat
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1380288-88-9 | Cat. No. | BCP14198 |
| Name | Pinometostat | ||
| Synonyms | EPZ-5676;EPZ5676;Pinometostat; | ||
| SMILES | NC1=NC=NC2=C1N=CN2[C@H]3[C@H](O)[C@H](O)[C@@H](CN([C@@H]4C[C@H](CCC5=NC6=C(C=CC(C(C)(C)C)=C6)N5)C4)C(C)C)O3 | ||
| Chemical Name | |||
| Formula | C30H42N8O3 | M. Wt | 562.71 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | EPZ-5676 is a potent and selective aminonucleoside inhibitor of DOT1L histone methyltransferase with Ki of < 80 pM, demonstrating > 37,000-fold selectivity against all other PMTs tested, and inhibits H3K79 methylation in tumor. | ||
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