Triphenylmethyl Irbesartan
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CAS No. | 138402-10-5 | Cat. No. | BCP12008 |
Name | Triphenylmethyl Irbesartan | ||
Synonyms | SR-47436; BMS-186295;SR 47436; BMS 186295;SR47436; BMS186295; | ||
SMILES | |||
Chemical Name | |||
Formula | C44H42N6O | M. Wt | 670.84 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Irbesartan is an angiotensin II receptor antagonist used mainly for the treatment of hypertension. It selectively and competitively blocks the binding of angiotensin II to the angiotensin I receptor. Angiotensin II stimulates aldosterone synthesis and secretion by adrenal cortex, which decreases the excretion of sodium and increases the excretion of potassium. Angiotensin II also acts as a vasoconstrictor in vascular smooth muscle. |
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