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Tenofovir alafenamide hemifumarate Chemical Structure

Tenofovir alafenamide hemifumarate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP24104CAS No. :1392275-56-7Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1392275-56-7 Cat. No. BCP24104
Name Tenofovir alafenamide hemifumarate
Synonyms GS-7340 hemifumarate;GS7340 hemifumarate ;GS 7340 hemifumarate;
SMILES CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3.CC(C)OC(=O)C(C)NP(=O)(COC(C)CN1C=NC2=C(N=CN=C21)N)OC3=CC=CC=C3.C(=CC(=O)O)C(=O)O
Chemical Name
Formula C46H62N12O14P2 M. Wt 1069.02
Purity 98% Storage Store at 4-8°C
Description Tenofovir alafenamide hemifumarate is a nucleotide reverse transcriptase inhibitor (NRTIs) and a novel prodrug of tenofovir. By blocking reverse transcriptase, TAF prevent HIV from multiplying and can reduce the amount of HIV in the body. Tenofovir alafenamide is a prodrug, which means that it is an inactive drug. In the body, tenofovir alafenamide is converted to tenofovir diphosphate (TFV-DP). Tenofovir alafenamide fumarate was approved in November 2015 for treatment of HIV-1.
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