N-Desmethyl Zolmitriptan New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 139264-35-0 | Cat. No. | BCP15367 |
| Name | N-Desmethyl Zolmitriptan | ||
| Synonyms | Zolmitriptan USP Related Compound A; | ||
| SMILES | CNCCC1=CNC2=C1C=C(C=C2)CC3COC(=O)N3 | ||
| Chemical Name | |||
| Formula | C15H19N3O2 | M. Wt | 273.34 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | N-Desmethyl Zolmitriptan is one of the impurities of Zolmitriptan.Zolmitriptan is a member of the triptan class agents with anti-migraine property. Zolmitriptan selectively binds to and activates serotonin (5-HT) 1B expressed in intracranial arteries and 5_HT 1D receptors located on peripheral trigeminal sensory nerve terminals in the meninges and central terminals in brain stem sensory nuclei. Receptor binding results in constriction of cranial vessels, reduction of the vessel pulsation and inhibition of nociceptive transmission, thereby providing relief of migraine headaches. Zolmitriptan may also relief migraine headaches by inhibition pro-inflammatory neuropeptide release. | ||
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