MTDIA HCl New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1399840-35-7 | Cat. No. | BCP20345 |
| Name | MTDIA HCl | ||
| Synonyms | MTDIA;Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl; | ||
| SMILES | NC(N=CN=C12)=C2NC=C1C[N+]3([H])C[C@@H]([C@H](C3)O)CSC.[Cl-] | ||
| Chemical Name | |||
| Formula | C13H20ClN5OS | M. Wt | 329.85 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Human 5'-methylthioadenosine phosphorylase (MTAP) is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer candidates. TS analogues of MTAP incorporate a cationic nitrogen and a protonated 9-deazaadenine leaving group, which are mimics of the ribocation transition state. MT-ImmA and MT-DADMe-ImmA are two examples of these TS analogues. | ||
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