TRV130 hydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1401031-39-7 | Cat. No. | BCP19171 |
| Name | TRV130 hydrochloride | ||
| Synonyms | TRV-130 hydrochloride;TRV 130 hydrochloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C22H31ClN2O2S | M. Wt | 423.01 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: In cell-based assays, TRV130 elicits robust G protein signaling, with potency and efficacy similar to morphine, but with far less β-arrestin recruitment and receptor internalization . in vivo: In mice and rats, TRV130 is potently analgesic while causing less gastrointestinal dysfunction and respiratory suppression than morphine at equianalgesic doses . Compared to morphine, TRV130 (3, 4.5mg) elicited higher peak analgesia (105, 116 seconds latency vs 75 seconds for morphine, P | ||
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