BMS-906024 New
Data Sheet
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| CAS No. | 1401066-79-2 | Cat. No. | BCP18995 |
| Name | BMS-906024 | ||
| Synonyms | BMS 906024;BMS906024;Osugacestat; | ||
| SMILES | CN1C2=CC=CC=C2C(=NC(C1=O)NC(=O)C(CCC(F)(F)F)C(CCC(F)(F)F)C(=O)N)C3=CC=CC=C3 | ||
| Chemical Name | |||
| Formula | C26H26F6N4O3 | M. Wt | 556.5 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BMS-906024 is a novel, potent Notch receptor inhibitor . Cancers have a tendency to relapse or to become resistant to treatments that once worked. A family of proteins called Notch is implicated in that resistance and in cancer progression more generally. BMS-906024 is in Phase I clinical trials, both alone and in combination with other agents. Patients with colon, lung, breast, and other cancers are receiving intravenous doses of the compound to determine its safety and optimum dose ranges. | ||
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