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CAS No. | 1401090-53-6 | Cat. No. | BCP20857 |
Related Products | 1629063-78-0(Ibiglustat succinate) | ||
Name | Ibiglustat | ||
Synonyms | Venglustat;GZ-402671; GZ402671; GZ402671; SAR402671; SAR-402671; SAR 402671; Genz-682452-AA;GZ-452; Genz-682452; | ||
SMILES | CC(C)(C1=CSC(=N1)C2=CC=C(C=C2)F)NC(=O)OC3CN4CCC3CC4 | ||
Chemical Name | |||
Formula | C20H24FN3O2S | M. Wt | 389.49 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Ibiglustat, also known as GZ402671, GZ-452; Genz-682452 and SAR402671, is a potent and selective Glucosylceramide synthase inhibitor and ceramide glucosyltransferase inhibitor. Ibiglustat blocks the formation of glucosylceramide (GL-1), a key intermediate in the synthesis of GL-3. Ibiglustat is potentially useful for treating Fabry disease. Fabry disease is a rare lysosomal storage disorder, which results in abnormal tissue deposits of a particular fatty substance called globotriaosylceramide (GL-3 or Gb3) throughout the body. |
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