GSK2879552
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1401966-69-5 | Cat. No. | BCP16137 |
| Name | GSK2879552 | ||
| Synonyms | GSK-2879552;GSK 2879552; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H28N2O2 | M. Wt | 364.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GSK2879552 is a selective, orally bioavailable, mechanism-based inactivator of lysine-specific demethylase 1 (LSD1)/corepressor for element-1-silencing transcription factor (CoREST) activity.Inhibition of LSD1 via GSK2879552 has been shown to enhance H3K4 methylation and to increase the expression of tumor-suppressor genes.GSK2879552 demonstrates anti-proliferative growth effects (EC50s = 2-240 nM) in AML cell lines and is currently under clinical evaluation for cancer treatment. | ||
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