Copanlisib Dihydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1402152-13-9 | Cat. No. | BCP19774 |
| Name | Copanlisib Dihydrochloride | ||
| Synonyms | BAY 80-6946 Dihydrochloride;Copanlisib HCl; BAY 80-6946; BAY80-6946; BAY-80-6946; BAY806946; BAY-806946; BAY 806946; Copanlisib; | ||
| SMILES | O=C(C1=CN=C(N)N=C1)NC2=NC3=C(OC)C(OCCCN4CCOCC4)=CC=C3C5=NCCN25.[H]Cl.[H]Cl | ||
| Chemical Name | |||
| Formula | C23H30Cl2N8O4 | M. Wt | 553.45 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Copanlisib also known as BAY 80-6946, is a potent phosphoinositide 3-kinase (PI3K) inhibitor. Copanlisib inhibits the activation of the PI3K signaling pathway, which may result in inhibition of tumor cell growth and survival in susceptible tumor cell populations. Activation of the PI3K signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K signaling may contribute to tumor resistance to a variety of antineoplastic agents. Copanlisib was approved for the treatment of adult patients experiencing relapsed follicular lymphoma who have received at least two prior systemic therapies. | ||
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