ML281
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1404437-62-2 | Cat. No. | BCP17565 |
| Name | ML281 | ||
| Synonyms | ML-281;ML 281; | ||
| SMILES | O=C1NC2=CC=CC=C2N=C1C3=CC(C(C)C)=CC=C3NC(C4=CC=CS4)=O | ||
| Chemical Name | |||
| Formula | C22H19N3O2S | M. Wt | 389.47 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ML-281 is a potent ans selective STK33 inhibitor (IC50 = 14 nM). ML281 showed low nanomolar inhibition of purified recombinant STK33 and a distinct selectivity profile as compared to other STK33 inhibitors. ML281 is a valuable addition to small-molecule probes of STK33. v-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog (KRAS) is the most mutated oncogene, and KRAS mutations have been found in up to 20% of all human tumors. STK33 was selectively toxic to KRAS-dependent cancer cell lines, suggesting that small-molecule inhibitors of STK33 might selectively target KRAS-dependent cancers. | ||
Recommend Products
More >
-
Tromethamine hydrochloride
Cat. No.：BCP49690
No.：1185-53-1
Product Details -
Hematin porcine
Cat. No.：BCP49671
No.：15489-90-4
Product Details -
β-Cyclodextrin
Cat. No.：BCP49653
No.：7585-39-9
Product Details -
α-Cyclodextrine
Cat. No.：BCP49652
No.：10016-20-3
Product Details -
-
H-Gly-hyp-ala-OH
Cat. No.：BCP49639
No.：62147-09-5
Product Details -
Cyanine 7 maleimide
Cat. No.：BCP49636
No.：2120392-49-4
Product Details -
Flavin adenine dinucleotide
Cat. No.：BCP49621
No.：146-14-5
Product Details -
-
-
-
Onilcamotide
Cat. No.：BCP49539
No.：1164096-85-8
Product Details -
-
-
3β-Ursodeoxycholic Acid
Cat. No.：BCP45877
No.：78919-26-3
Product Details -
Vutrisiran
Cat. No.：BCP45179
No.：1867157-35-4
Product Details -
Sodium carboxymethyl cellulose
Cat. No.：BCP43883
No.：9004-32-4
Product Details -
-
Tosylate-DPA-714
Cat. No.：BCP39586
No.：958233-17-5
Product Details -
Coelenterazine H
Cat. No.：BCP10701
No.：50909-86-9
Product Details
Tags:ML281 supplier,ML281 purchase,ML281 manufacturer,ML281 distributor,ML281 cost,ML281 buy,ML281 for sale