Polymyxin B sulfate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1405-20-5 | Cat. No. | BCP12700 |
| Name | Polymyxin B sulfate | ||
| Synonyms | KS-1428; KS 1428; KS1428; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C56H100N16O17S | M. Wt | 1301.56 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Polymyxin B sulfate is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic. They bind and kill Gram-negative bacteria.2 The B series of polymyxins consist of a cyclic heptapeptide and a tripeptide side chain acylated at the amino terminus by a fatty acid. Polymyxin B (sulfate) is a mixture of at least four closely related components, polymyxin B1 to B4, with polymyxin B1 (Item No. 14074) and B2 being the two major components. | ||
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