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CAS No. | 141400-58-0 | Cat. No. | BCP08978 |
Name | PX12 | ||
Synonyms | PX 12; PX-12;IV-2;IV2;IV 2; | ||
SMILES | |||
Chemical Name | |||
Formula | C7H12N2S2 | M. Wt | 188.31 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PX-12 is an irreversible inhibitor of Trx-1 currently in clinical development as an antitumor agent. The research results suggest that the lowering of elevated levels of plasma Trx-1 in cancer patients may provide a surrogate for the inhibition of tumor Trx-1 by PX-12. Furthermore, PX-12 decreases plasma VEGF levels which may contribute to the antitumor activity of PX-12. |
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