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CAS No. | 1431326-61-2 | Cat. No. | BCP16138 |
Name | Ladademstat dihydrochloride | ||
Synonyms | ORY-1001 2HCl;RG6016 2HCl; RO 7051790 dihydrochloride;ORY 1001;ORY1001;RG6016;RG-6016;RG 6016;LSD1-IN-1; | ||
SMILES | C1CC(CCC1N)NC2CC2C3=CC=CC=C3.Cl.Cl | ||
Chemical Name | |||
Formula | C15H24Cl2N2 | M. Wt | 303.27 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ORY-1001 is an orally available, selective inhibitor of LSD1 (IC50 < 20 nM).It targets acute myeloid leukemia (AML) stem cells and significantly reduces tumor cell load while increasing survival time in mouse models of AML. |
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