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GDC-0853
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CAS No. | 1434048-34-6 | Cat. No. | BCP19175 |
Name | GDC-0853 | ||
Synonyms | GDC0853;GDC 0853;Fenebrutinib; RG-7845; RG7845; RG 7845; | ||
SMILES | |||
Chemical Name | |||
Formula | C37H44N8O4 | M. Wt | 664.8 |
Purity | 98% | Storage | Store at 4-8°C |
Description | GDC-0853 inhibits the activity of BTK and prevents the activation of the B-cell antigen receptor (BCR) signaling pathway. This prevents both B-cell activation and BTK-mediated activation of downstream survival pathways, which leads to the inhibition of the growth of malignant B-cells that overexpress BTK. |
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