YYA-021
Data Sheet
For research use only. Not for human use.
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| CAS No. | 144217-65-2 | Cat. No. | BCP18096 |
| Name | YYA-021 | ||
| Synonyms | YYA021;YYA 021; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C18H27N3O2 | M. Wt | 317.43 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | IC50 (=8.4 μM) value of YYA-021 is determined by a single round assay using cYTA48P virus and TZM-bl cells. YYA-021 is broadly distributed in tissues, probably as a result of its hydrophobicity. The plasma concentrations of YYA-021 in both species remained at micromolar levels for several hours post-injection. YYA-021 also enhances the neutralizing activity of KD-247 against simian-human immunodeficiency virus (SHIV)-KS661 strain via highly synergistic interactions. YYA-021 might have promise as a lead compound for the intravenous administration in a cocktail therapy with anti-gp120 monoclonal antibodies such as KD-247 and with co-receptor antagonists such as T140. | ||
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