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MK8742 Chemical Structure

MK8742

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP09464CAS No. ：1444832-51-2Purity：98%
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  • Chemical Properties&Biological Activity
CAS No. 1444832-51-2 Cat. No. BCP09464
Name MK8742
Synonyms Elbasvir;MK-8742;MK 8742;Elbasvir intermediate;Elbasvir-D6;
SMILES CC(C)[C@@H](C(=O)N1CCC[C@@H]1C2N=CC(=N2)C3=CC4=C(C=C3)C5=CC6=C(N5[C@@H](O4)C7=CC=CC=C7)C=CC(=C6)C8=CN=C(N8)[C@@H]9CCCN9C(=O)[C@H](C(C)C)NC(=O)OC)NC(=O)OC
Chemical Name
Formula C49H55N9O7 M. Wt 882.04
Purity 98% Storage Store at 4-8°C
Description Elbasvir, also known as MK-8742, is a HCV NS5A inhibitor, which is currently in phase 2b clinical trials as part of an all-oral, interferon-free regimen for the treatment of HCV infection. The NS5A protein plays a critical role in the replication of HCV and has been the focus of numerous research efforts over the past few years. NS5A inhibitors have shown impressive in vitro potency profiles in HCV replicon assays, making them attractive components for inclusion in all oral combination regimens.
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