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Lu AF21934 Chemical Structure

Lu AF21934

Data Sheet For research use only. Not for human use.
Cat. No. :BCP20740CAS No. :1445605-23-1Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1445605-23-1 Cat. No. BCP20740
Name Lu AF21934
Synonyms Lu AF-21934; Lu AF 21934; Lu-AF21934; Lu-AF-21934; Lu-AF 21934;
SMILES
Chemical Name
Formula C14H16Cl2N2O2 M. Wt 315.2
Purity 98% Storage Store at 4-8°C
Description Lu AF21934 is a positive allosteric modulator of mGlu4 receptors. Lu AF21934 reduces the harmaline-induced hyperactivity but not tremor in rats. The actions of Lu AF21934 are 5-HT1A receptor-dependent. Activation of the mGlu4 receptor may be a promising mechanism for the development of novel antipsychotic drugs, efficacious toward positive, negative, and cognitive symptoms.
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