Voxelotor New
Data Sheet
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| CAS No. | 1446321-46-5 | Cat. No. | BCP20182 |
| Name | Voxelotor | ||
| Synonyms | GBT-440;GBT440;GBT 440;GTx-011;GTx011;GTx 011; | ||
| SMILES | OC1=CC=CC(OCC2=C(C3=CC=NN3C(C)C)N=CC=C2)=C1C=O | ||
| Chemical Name | |||
| Formula | C19H19N3O3 | M. Wt | 337.37 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GBT-440 is a hemoglobin S allosteric modulator. GBT440 Inhibits Sickling of Sickle Cell Trait Blood Under In Vitro Conditions Mimicking Strenuous Exercise. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. GBT440 increases haemoglobin oxygen affinity, reduces sickling and prolongs RBC half-life in a murine model of sickle cell disease. | ||
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