Pixantrone Maleate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 144675-97-8 | Cat. No. | BCP07678 |
| Name | Pixantrone Maleate | ||
| Synonyms | BBR 2778; BBR2778; BBR-2778; Pixantrone; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C17H19N5O2.2(C4H4O4) | M. Wt | 441.44 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pixantrone dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity.Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). | ||
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