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Futibatinib Chemical Structure

Futibatinib

Data Sheet For research use only. Not for human use.
Cat. No. :BCP17213CAS No. :1448169-71-8Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1448169-71-8 Cat. No. BCP17213
Name Futibatinib
Synonyms Tas120;Tas-120;Tas 120;FGFR-IN-1;
SMILES COC1=CC(=CC(=C1)C#CC2=NN(C3=NC=NC(=C23)N)C4CCN(C4)C(=O)C=C)OC
Chemical Name
Formula C22H22N6O3 M. Wt 418.5
Purity 98% Storage Store at 4-8°C
Description Futibatinib is an orally bioavailable inhibitor of the fibroblast growth factor receptor (FGFR) with potential antineoplastic activity. Futibatinib selectively and irreversibly binds to and inhibits FGFR, which may result in the inhibition of both the FGFR-mediated signal transduction pathway and tumor cell proliferation, and increased cell death in FGFR-overexpressing tumor cells. FGFR is a receptor tyrosine kinase essential to tumor cell proliferation, differentiation and survival and its expression is upregulated in many tumor cell types.
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